Indomethacin Prescription: What You Need to Know

If your doctor talked about indomethacin, you probably wonder why it’s needed and how to use it safely. It’s an NSAID that works hard on pain and inflammation, especially for arthritis, gout, and certain kinds of headaches. Below you’ll get the basics without any medical jargon.

Dosage and How to Take Indomethacin

Most adults start with 25 mg two or three times a day. Your doctor might increase the dose to 75 mg daily for tougher cases, but never go above 200 mg in a day unless a specialist says it’s okay. Take the tablets with food or a full glass of milk to cut stomach irritation.

If you miss a dose, take it as soon as you remember—unless it’s almost time for the next one. In that case, skip the missed tablet; don’t double up. Consistency matters, so try to take it at the same times each day.

Side Effects and Interactions

Common side effects include stomach upset, nausea, and mild headache. Watch for any stomach pain that feels sharp or any black‑tarry stools—those can signal bleeding and need immediate medical attention.

Indomethacin can raise blood pressure, so keep an eye on your numbers if you already have hypertension. It also interacts with blood thinners like warfarin, some antidepressants, and other NSAIDs. Tell your doctor about every medication, supplement, or over‑the‑counter product you use.

Kidney function can take a hit, especially in older adults or people with existing kidney disease. If you notice swelling in your ankles or sudden weight gain, call your doctor.

Alcohol can worsen stomach irritation, so limit drinks while on the medication. Smoking doesn’t directly affect indomethacin, but it can worsen the conditions it’s meant to treat.

When you finish the prescription, don’t just stop abruptly if you’ve been on it for weeks. Talk to your doctor about tapering down to avoid rebound pain.

Pregnant or breastfeeding women should avoid indomethacin unless the doctor says the benefits outweigh the risks. It can affect the fetal heart and reduce amniotic fluid.

Storage is simple: keep the bottle in a cool, dry place, away from direct sunlight. Keep it out of reach of children.

Finally, keep a list of any side effects you experience and share it with your healthcare team during follow‑up visits. This helps them adjust the dose or switch to another drug if needed.

Indomethacin can be a powerful tool for controlling pain, but it works best when you understand how to take it safely. Use it with food, monitor for side effects, and keep your doctor in the loop. That way you’ll get relief without unnecessary risks.

14

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